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UOA 44 - Psychology

University of Edinburgh

RA1, RA2 and RA5c: Staff and output details and Category C staff circumstances

 

Abrahams, S - Category : A

RA2 - Research outputs:

Number of outputs: 4

Output number: 1 of 4

Title
Cognitive change in Amytrophic Lateral Sclerosis: a prospective study
Output type: Journal article
Journal title: Neurology
Month/year of publication: April 2005
Pagination: 1222-1226
Volume: 64(7)
ISSN: 0028-3878
DOI: Not supplied ?
Co-authors: Goldstein, L.H. , Leigh, P.N.
Other relevant details: This was the first major longitudinal study of cognition in ALS, demonstrating cognitive deficits early in the disease process, but no rapid degeneration of cognition or progression into dementia despite clear progression in motor symptoms. The research was funded through a Wellcome Trust Fellowship held by Abrahams who generated the ideas for the study, undertook most of the data collection and analysis and the bulk of the writing. Goldstein was a senior neuropsychologist, contributing to initial design, analysis and write up. Leigh was a clinician providing access to patients, contributing to initial design and final write up.

Output number: 2 of 4

Title
Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study
Output type: Journal article
Journal title: Brain
Month/year of publication: July 2004
Pagination: 1507-1517
Volume: 127(7)
ISSN: 0006-8950
URL: Original article on web ?
DOI: 10.1093/brain/awh170 ?
Co-authors: Brammer, M. J., Goldstein, L.H. , Simmons, A.
Number of additional co-authors: 3
Other relevant details: This paper demonstrated for the first time functional changes in language pathways in ALS patients using fMRI, and evidence of extensive extra-motor involvement in ALS. It was funded through a Wellcome Trust Fellowship held by Abrahams who generated the ideas for the study, undertook most of the data collection and analysis and the bulk of the writing. Goldstein was a neuropsychologist, contributing to design, analysis and write up. Leigh was a clinician providing access to patients, contributing to design and write up. Other authors contributed practical aspects of design and analysis of MRI data.

Output number: 3 of 4

Title
Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses
Output type: Journal article
Journal title: Human Brain Mapping
Month/year of publication: July 2003
Pagination: 29-40
Volume: 20(1)
ISSN: 1065-9471
DOI: 10.1002/hbm.10126 ?
Co-authors: Brammer, M.J. , Goldstein, L.H. , Simmons, A.
Number of additional co-authors: 4
Other relevant details: This paper was the first to demonstrate a new technique for investigating patients using functional MRI. The technique allowed patients to speak whilst being scanned. This study was funded through a Wellcome Trust Fellowship held by Abrahams who generated the ideas for the study, undertook most of the data collection and analysis and the bulk of the writing. Goldstein was a neuropsychologist contributing to design, analysis and write up. Leigh was a clinician providing access to patients, contributing to design and write up. Other authors contributed practical aspects of design and analysis of MRI data.

Output number: 4 of 4

Title
Frontotemporal white matter changes in amyotrophic lateral sclerosis
Output type: Journal article
Journal title: Journal of Neurology
Month/year of publication: March 2005
Pagination: 321-331
Volume: 252(3)
ISSN: 0340-5354
URL: Original article on web ?
DOI: 10.1007/s00415-005-0646-x ?
Co-authors: Goldstein, L.H. , Ng, V. , Suckling, J.
Number of additional co-authors: 5
Other relevant details: This paper was the first to demonstrate evidence of white matter changes in extra-motor regions in ALS patients. Such changes may underlie the cognitive and functional imaging changes previously reported. This study was funded through a Wellcome Trust Fellowship held by Abrahams. Abrahams generated the ideas for the study, undertook the analysis and the bulk of the writing. Suckling helped with MRI analysis. Goldstein was a neuropsychologist contributing to design, analysis and write up. Leigh was a clinician providing access to patients, contributing to design and write up. Other authors contributed practical aspects of design and analysis of MRI data.