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UOA 25 - General Engineering and Mineral & Mining Engineering
University of Strathclyde
RA5a: Research environment and esteem
Our research is focused on improving health and life quality through fundamental and applied research based on:
Multidisciplinary research groups;
Sustainable collaborations with representative users;
A vibrant, modern environment for training researchers.
Bioengineering has deliberately placed itself at the centre of a multidisciplinary research activity uniting science, engineering and medicine. A new Institute and Doctoral Centre introduced since 2001 (see 1.1) have ensured that the core strengths of the department in rehabilitation, cell & tissue engineering and medical diagnostics have been recognised in numerous research programmes and collaborations in the last 6 years. We have gained SRIF investment of >£1.5M during this period to further develop our state-of-the-art laboratories and clinical test facilities and have elected to be part of the SFC engineering research pooling programme (Glasgow Research Partnership in Engineering, GRPE £15M). We have taken a leading role within the University and Faculty in the area of health research and have established strong partnerships with the NHS and industry.
Our strategy is aligned with key reports identifying the need for multidisciplinary approaches to health research and changing demographics (particularly Foresight, UK TSB, HITF, Cooksey). Accordingly, we have engaged in initiatives that include the EPSRC EQUAL programme and the BBSRC/EPSRC capacity building initiative in age-related research (SPARC).
We remain committed to the generation of fundamental and applied research of international significance. Our international activities cover academic and industrial research and scholarly activities (see 1.3 and 2.0). The Bioengineering Unit is well-recognised globally in the sector.
Our activities support the translation of promising results into healthcare practice and devices and we believe we are ideally positioned to respond to the future translational and applied health research needs of end-user communities.
1.1 Evaluation of RAE2001 Plans
In RAE2001, our planning focussed on building research and postgraduate training in medical devices. This approach was supported by the appointment of Prof Connolly (1999) from the medical device industry. Key achievements have been the establishment of the first EPSRC Doctoral Training Centre (DTC) for Medical Devices (2003) and the launch in 2006 of the Strathclyde Institute for Medical Devices (SIMD) as proposed in RAE2001.
EPSRC funding for the renewal of our DTC award (~£3.6M) has recently been approved and this will further strengthen medical device research.
SIMD is funded by the University and Scottish Enterprise and is a key component in our strategic research development with the NHS and industry. The initial success of SIMD has led to the formation of the Glasgow Health Technology Cooperative, a joint venture with NHS Greater Glasgow.
SIMD and the DTC have continued to progress and unite the key areas of Bioengineering research as described in 2001. In fact through these activities, Bioengineering has become the core of an interdisciplinary network covering science, engineering and medicine subscribed to by some 60 academics and 30 clinicians who participate in DTC and SIMD projects and events.
1.2 Research Management.
An executive committee chaired by the Head of Department develops research strategy. This committee reports bimonthly to academic staff and provides a mechanism for the development of policy and strategic planning which bridges research, teaching, facilities and finance. The committee members also attend other University committees including the Faculty’s Research Committee and the GRPE.
1.3 Research Structure.
Our current research activities derive from the four research groups returned in RAE2001. However, in response to staff changes our research has been consolidated into three groups as follows.
1.3.1 Rehabilitation Engineering: (Nicol, Conway, Spence, Stanfield, Riches, Lakany)
Research activity continues in three areas:
-Prosthetics and Orthotics
-Motor control and Neuroprosthetics
Biomechanics research (Nicol, Stansfield, Riches).
Strengths exist in the development of advanced 3D biomechanical models of joint function that incorporate MRI and mechanical testing of human tissue. Collaboration has been established with the Golden Jubilee Hospital (Clydebank) and funding (Furlong Foundation) has been secured to further develop wrist biomechanics related to Computer Navigated Surgery.
Projects with Glasgow Royal Infirmary are underway to determine patient performance/function with joint replacements. Stryker UK supports this via a studentship and a research manager/facilitator who coordinates research activities of orthopaedic staff in liaison with the rehabilitation engineering group. Key work in this area stems from an EPSRC study using telemetry to measure the loadings on replacement hip joints during everyday activities. This seminal study (rated as ‘Tending to Outstanding’) was performed in collaboration with the Free University of Berlin.
Biomechanics research also includes projects aimed at understanding how people do everyday tasks. This work ranges from activity monitoring to multidisciplinary projects on ageing and inclusive design. Here EPSRC (EQUAL) funding has led to a unique way of incorporating complex joint loading data into computer animations allowing designers to assess the suitability of products for use by the elderly. Rated as ‘Tending to Outstanding’, the project involved collaboration with The Glasgow School of Art, Psychology (Strathclyde) and the Health Faculty, Queen Margaret College University Edinburgh. Development of this work will proceed via a New Dynamics of Ageing award led by Glasgow School of Art and a capacity building award (SPARC) investigating loadings in packaging for use by the elderly (Stansfield). Research examining environmental influences on mobility in the elderly (Riches) has also taken place and will continue.
Mathematical models of intervertebral discs have progressed that inform on normal disc functioning and its transfer to aged and diseased conditions. Work demonstrating the importance of strain dependency on the disc’s permeability and of osmosis for disc nutrition led to an EPSRC first grant award (Riches) that allows links between disc biomechanics and low back pain to be better understood.
Prosthetics and Orthotics (Spence, Nicol)
Evaluation of the prosthetic leg and foot is a programme employing varied methodologies (FEA, MRI, interface pressure measurement and 3D-ultrasound). Measurement needs in this field often require the construction of specialized transducers. For example, collaboration through the Kelvin Institute (a knowledge transfer organisation) has led to the development of low-cost imaging technology that can accurately image the shape of the residual limb and aid in the manufacture of bespoke sockets. Strong links with industry (Blatchfords, Otto-Bock) and the NHS are established.
Motor control and Neuroprosthetics (Conway, Lakany).
Spinal cord injury (SCI) research has continued since RAE2001 and centres on the development of diagnostic tests for use in clinical trials associated with regenerative treatments and novel rehabilitation protocols. These projects rely on the use of advanced electrophysiological measurements and analysis.
Funding for this research arises from the Clinical Initiative programme of the International Spinal Research Trust. The consortium involves Imperial College, University of Alberta, Balgrist Hospital Zurich, the Queen Elizabeth National Spinal Injuries Unit (QENSIU) and the Centre for Rehabilitation Engineering (CRE, University of Glasgow). Related to this work is our research on robotic assisted gait rehabilitation (Lokomat, http://www.hocoma.ch) which is set to become an important element for our future gait restoration projects in SCI.
SCI research activities are embedded in the QENSIU where new research facilities and infrastructure are under development (supported by NHS, CRE and GRPE). Longstanding reciprocal collaboration also continues with the University of Copenhagen exploring the neurophysiological mechanisms relevant to gait rehabilitation.
Work in neuroprosthetics has expanded to include developments in Brain Computer Interfacing (BCIs). BCIs use electroencephalography (EEG) to drive assistive devices. Work on the classification of EEG signals for device commands is showing promise and a BCI for use by paralysed patients will be developed over the next 5 years. A MRC discipline hopping grant (Lakany) in this field was instrumental in establishing this new venture.
Expertise in EEG has also opened new work in dementia. Due to commence in 2008 this collaboration (Kilborn, Psychology, University of Glasgow and Geriatric Psychiatry) is funded by the Translational Medicine Research Collaboration (Wyeth Pharmaceuticals).
1.3.2. Medical Diagnostic Devices & Instrumentation (Connolly, Gourlay)
Research activity has grown in the three main areas identified in RAE2001:
-Sensors for cell & tissue engineering/implanted devices
-Rapid blood sensors/non-invasive diagnostics
Since 2001, significant effort has been devoted to understanding the needs of end-users, securing IP and encouraging healthcare and commercial partnerships.
In minimally invasive diagnostics, progress on wound hydration systems has provided a new wound bed model that simulates the conditions encountered by advanced wound dressings. Using this, Connolly developed an impedance sensor system allowing hydration profiles across dressings to be characterised. Convatec assessed the system with their new wound dressing, Versiva. A unique disposable sensor array has now been produced for use under any wound dressing, allowing monitoring without dressing removal. In 2007, a clinical trial commenced (NHS Greater Glasgow & Clyde) and confirmed that the device can detect wound hydration states. This device should have a significant impact on wound research and management. Patent application is in progress.
In implanted devices, a new porcine in-vitro model for monitoring restenosis in cardiac stents has been developed. Results will be disseminated following patent applications. With the recruitment of Gourlay a programme of work aimed at bringing implantable intelligent sensors into medical devices has been strengthened. Electronic engineers at the University of Strathclyde (Stewart, Glover) have pledged their support to projects which use wireless telemetry to communicate with chronically implanted sensors. Initial experiments are promising and a translational research programme monitoring a range of cardiac devices is planned with the University of Lille.
Utilisation of rat models of open-heart surgery has led to international recognition and collaborative opportunities. Gourlay, together with the University of Lille, has exploited these models to investigate the cerebrovascular consequences of cardiopulmonary bypass establishing the link between early inflammatory events and cerebral injury (3 PhDs completed). Work of clinical significance focusing on inflammation and developing associated diagnostic markers is ongoing.
Another rat model has been developed to investigate biomaterials and has been the focus of considerable research effort, leading to the demonstration of the pro-inflammatory effects of DEHP, a plasticiser commonly employed in medical grade PVC. Work is continuing in collaboration with Hydro Polymers to investigate new plasticisers for clinical applications.
In iontophoresis (non-invasive diagnostics) diagnostically relevant concentrations of glucose and lactate can be extracted simultaneously from the skin of volunteers without blood sampling. Device trials are planned with collaborators from Leeds General and Glasgow Royal Infirmary (intensive therapy, plastic surgery and vascular disease).
Developments continue in nano-structured ceramics for extracoporeal treatment of inflammatory conditions. With DTI support (£1.13M) to Gourlay, University of Brighton and Mast Carbon Ltd, we aim to deliver technology for removing pro-inflammatory cytokines from patients with inflammatory conditions. A catalyst has been developed as a near-real-time diagnostic and monitoring technology for cytokines. Here clinical collaboration with the Hammersmith Hospital has focused on the identification of biomarkers and diagnostic technology. We anticipate that the combination of biochemical measurement and targeted therapeutic technologies offer potential for novel interventional strategies with applications in hyperlipidaemia, crush and reperfusion injury. Current collaborations include University Hospital Leeds, Hammersmith Hospital, University of Kirkkale (Turkey) and the University of North Texas. Joint patent applications are being filed and work continues on the associated diagnostic technology.
Further collaborative effort (Hammersmith Hospital, Imperial College, Glasgow Royal Infirmary) into laser blood flow imaging (Moor Instruments) as a diagnostic tool in cardiovascular surgery is ongoing. Early results suggest high sensitivity in the identification of early graft blockage.
1.3.3. Cell, Tissue and Organ Engineering (Grant, Gaylor, Black)
Projects continue in line with RAE2001. Of note are projects on the effects of metal implants on cellular function, work on cell engineering, hybrid artificial organs, and cardiovascular related bioengineering.
Expertise on the cytotoxic effects of chromium has led to membership (Grant) of the MHRA Expert Group on the biological effects of metal-on-metal (MOM) implants. MOM implants for hip replacement are being used in younger patients exposing them to metallic ions and debris for >50 years. Our ground-breaking work on chromium leakage from MOM implants, its distribution in the blood and interactions with osteoblasts, macrophages and hepatocytes has made a substantial contribution to determining the long-term biological safety of MOM implants. This work is supported by De Puy International.
Tissue engineering scaffolds are being developed based on collagen for soft tissues and hydroxyapatite composites for bone (Grant). Our data showing the growth of immortalised osteoblasts in hyroxyapatite/tricalcium phosphate matrices enabled Dytech Company to obtain a CE mark for their synthetic bone material Synhapor. Pulsed Electric Field, originally developed in the University of Strathclyde for sterilising liquids in the food industry, is being applied to sterilisation of collagen-based gel matrices (Grant). This will permit sterilisation of matrices containing labile biological molecules, and provide a drug delivery method for genes and their products. Collaboration with the department of Electronic and Electrical Engineering and Dytech Company Limited is underway.
Optimisation of hepatocyte isolation techniques are being developed for use in toxicity testing in the pharmaceutical industry (Organon) based on our pioneering liver cell cryopreservation work (BBSRC).
Research has also addressed the study of the physical and biological properties of arterial substitutes that incorporate extracellular matrix molecules and vascular cells, and the bioreactors in which these tissues are formed and preconditioned in-vitro (Black). An international patent application has been filed for a rotating wall vessel bioreactor and work is underway to improve the licensing position of the technology. The application of computer-aided design and manufacturing techniques to anatomical modelling, implant design and manufacture is also of major interest. In developing arterial phantoms based on medical images generated by MRI and CT we have provided clinicians with the means to determine more accurately the flow structures present within blood vessels (carotid and femoral arteries) in health and disease. The work was carried out in collaboration with Medical Physicists (Edinburgh University) with EPSRC funding and combined research strengths in haemodynamics and medical imaging with state-of-the-art manufacturing technology.
Major refurbishments of laboratories, teaching, seminar, RA and PhD office spaces were completed in the RAE period.
Rehabilitation Engineering Enhancements
SRIF1: Refurbishment of Human Biomechanics Laboratories (2002). This created a highly accessible, well equipped, adaptable research environment catering for studies on normal and disabled volunteers. (Spend =£550K).
SRIF3: £275K for state-of-the-art equipment for BCI research (2005). The new equipment has been installed in a refurbished neurophysiology laboratory.
HealthQWest is a consortium involving West of Scotland healthcare professionals. Bioengineering is a member of this consortium with a remit to develop research in “Function for Living”- a theme allied to our research strategy. HealthQWest funding commenced in 2005 and supports staff and equipment. (HealthQWest staff have been returned under UOA 12.)
Glasgow Research Partnership in Engineering (GRPE). £450K has been made available to Rehabilitation Engineering through this initiative. This created a lectureship (Lakany, 2007) and funding for a RA, studentships and equipment. As part of GRPE we are closely allied with the research activities of Prof Hunt (CRE, University of Glasgow), Prof Granat (Caledonian University) and the QENSIU.
Cell, Organ & Tissue Engineering and Medical Diagnostic Devices & Instrumentation Enhancements.
The appointments of Gourlay and Black (both 2007) through the University’s Research Excellence Fund are designed to enhance and support activities in medical diagnostics and tissue engineering. This scheme awarded £500k for salaries, additional laboratory space and equipment.
SRIF 2 was secured to redevelop cell and tissue laboratories. Total spend exceeded £600k and new laboratories for cell and tissue engineering, medical devices and tissue testing (>600m2) completed (2004).
SRIF 3 provided £300k for a new, collaborative wireless implantable sensors laboratory based in Electronics (2006).
1.6 Provision of training and facilities for Research Students.
EPSRC funding of the DTC in Medical Devices was utilized with matched funding from the University to establish a DTC and PhD study area (2003). This facility comprises hot-desking accommodating 20 students in an open plan office environment (>150m2). Each student from the DTC is provided with a laptop. Bioengineering also provides a cluster of PCs for research student use.
All research students maintain a personal development plan and are reviewed annually in line with QAA codes of practice. A full programme of in-house generic skills training is provided with support from the Faculty, Learning Services and the Centre for Academic Practice. All research students are encouraged to attend residential UKGradSchool events.
Students are expected to present to at least one international conference and funds are made available to assist attendance.
1.7 Arrangements for Supporting Collaborative and Interdisciplinary Research.
We have a long history of working with NHS, academic and industrial partners based on the research networks of our staff. Collaboration and exchanges with leading international centres are highly encouraged.
Formal arrangements include a NIH funded training visit by Dr Erin (Rehabilitation Institute, Chicago) to work with Conway. Conway’s laboratory also partnered a MRC discipline hopper (Lakany) and hosted, and provided data to a PhD student from Brillinger’s group (University of Berkeley). A history of collaboration (Royal Society, Danish MRC) has existed between Conway and the University of Copenhagen.
Strong links with University of North Texas (Gourlay) exist and an exchange programme with the Laboratory for Cardiopulmonary Bypass Research (University of Lille) will be instrumental in establishing Bioengineering as the hub for multi-centred trials on lymphocyte filtration during cardiopulmonary bypass.
In medical devices, Dr. Ching (RA with Connolly) was the first Medical Devices Faraday Partnership Medical Devices Colorado Fellow and received training in entrepreneurship within the Colorado bio-cluster. He subsequently won a Royal Society of Edinburgh Enterprise Fellowship and has now secured a University position in Taiwan. Dr McColl (RA with Connolly) was invited to spend six months with the Sysmex Corporation (Japan) a major healthcare company supplying the blood diagnostics sector. In 2006, Prof Connolly hosted Dr Pisanowska from the Warsaw Institute in Medical Biosensors (funded via the Royal Society of Edinburgh) and provided training in biosensor development.
Bioengineering also attracts exchanges from visiting scientists and we are keen to develop these through our network of home based and foreign graduates. The Bioengineering research groups have also hosted visiting researchers from around the world including Columbia, France, Poland, Eire, Canada, Hong Kong and Singapore.
As a member of GRPE and HealthQWest, Bioengineering is well engaged in collaborative academic and clinical research in Scotland. Further opportunities to expand on this type of consortia are expected to emerge through the Scottish Research Partnership in Biomedical Engineering Technologies and draft submissions have been prepared (Gourlay, Connolly) for the SFC.
We also facilitate collaboration through our MRes (Biomedical Engineering) and our DTC programmes. All MRes and DTC research projects require co-supervision from academics from different disciplines; we also require that each project has a clinical or industrial link. Through the DTC we support 32 projects with supervisory input from 5 departments within Strathclyde, 5 separate universities, 20 clinical centres and a host of industrial partners. The DTC is in its 5th year and we are seeing promising projects producing sustained collaborations, joint IP and grant applications.
1.8 Arrangements for supporting relationships with end-users.
The activities of the SIMD are beginning to significantly influence collaboration through the newly formed Glasgow Health Technology Cooperative and via the KTN in Health Technologies. A Clinical Coordinator and Industrial Manager are employed by SIMD to facilitate NHS and industrial interaction. The SIMD website (www.strath.ac.uk/simd) is a first point of contact for many companies and clinicians.
In addition, engagement with end-users is facilitated by the University of Strathclyde’s Research and Innovation (R&I)service and the collaborations of each staff member. Close links with user groups have been a feature of a number of our EPSRC awards, in particular those funded under the EQUAL calls.
1.9 Arrangements for supporting commercialisation.
The main processes for research commercialisation are handled by R&I in conjunction with SIMD (Industrial Manager). R&I staff specialise in patent protection, licensing, company formation and managing of translation research activity. We have been involved with the Scottish Enterprise Proof of Concept (PoC) programme providing funding for innovative, early-stage technical concepts and their translation into business/commercialisation opportunities.
Where appropriate, the University’s Business Ventures Group provides start-up investment via the University’s Synergy Fund (£4M) and will in future be able to access the Strathclyde Innovation Fund (A University partnership with Braveheart Investment Group to establish a £12M fund).
1.10 Staffing Policy
Post RAE2001, two senior staff (Barbenel, Courtney) retired and a third took an appointment elsewhere (Granat). Nevertheless, our staff numbers have grown. In 2001, Stansfield was appointed with responsibility to develop biomechanics teaching and research. In 2006/7, a chair and senior lectureship (Gourlay, Black) were gained via the University’s Research Excellence Fund and a further lectureship (Lakany) acquired via GRPE funding. All new staff have start-up funding and reduced teaching and administration duties.
Staff development is encouraged through membership of our research groups and a mentoring scheme operates for new staff. Our aim is for all staff to achieve Principal Investigator status. 3-year research plans are required from all staff and are reviewed by the Head of Department. Staff training courses in research engagement are available through the University’s service departments.
Research is aided by 9 technicians, an IT officer and administrative staff. In-house facilities include mechanical and electronic workshops.
1.11 Group Vitality
Table includes Nov07 graduations but not data associated with ex-staff.
Refereed Conference Papers
Medical Devices & Diagnostics
Cell, Tissue &
2.1 Departmental Esteem.
EPSRC DTC in Medical Devices.
Strathclyde Institute of Medical Devices.
And is a member of:
Glasgow Health Technology Cooperative.
Health Technology KTN
Glasgow Research Partnership in Engineering.
EPSRC College Membership
Roshan Maini, Director, Vastutek-Terumo, UK.
Allan Ritchie, Vice-President, R&D, DePuy International.
Shervanthi Homer-Vanisinham, Consultant Vascular Surgeon & Sub-Dean, University of Leeds.
Mehdi Tavakoli, Programme Manager, Health Technology KTN.
JP Paul (Biomechanics) chairs the ISO sub-committee on Bone and Joint Replacement and is an editor for the Journal of Biomechanics, Prosthetics and Orthotics International and Human Movement Science. He has published 20 articles since 2001.
He is a fellow of:- RAEng, RSE. IMechE, ISPO, IPEM and the British Orthopaedic Association.
JM Courtney (Biomaterials) was awarded the Swinburne Award (2004) and has published 6 papers since 2001.
2.2 Staff Esteem
2001 British Society for Matrix Biology, Manchester.
2001 CLRC Workshop, Daresbury Laboratory.
2002 Models and Advances in Vascular Bioengineering, BRITEnet meeting.
2003 DTI-LGC Biomaterials Partnership, Cambridge
2003 Biomaterials Network meeting, Manchester.
2003 28th Annual Biomaterials Meeting, Leeds.
2005 Gordon Research Conference, NIH, U.S.A.
2006 EXPERTISSUES, Buxton.
2002 IEEE-EMBS Molecular , Cellular and Tissue Engineering, Genoa.
2003 UK Biomaterials Network Annual Meeting
2003 Annual International Perfusion Workshop, London.
2003 Eurobiochips, London
2005 Euronano Conference, Edinburgh
2001- EPSRC EQUAL Research Network Launch, Birmingham.
2003- International Society Brain Electromagnetic Topography, Santa Fe, USA.
2006- 35th American Aging Association Meeting. Boston, USA.
2006- Spinal Cord Injury Repair Workshop, UCL, UK.
2006 Esteemed Lecturer Series, Fort Worth Medical Centre, USA.
2001 Funding for Biological Sciences, Scottish Universities Group
2001 British Science Festival Lecture, Cells and Genes in Healthcare BBSRC Workshop
2002 Annual Conference of British Society for Histocompatibility and Immunogenetics
2002- UK Computing Research Committee, Edinburgh
2003- Fredrich-Alexander Universitaet, Germany
2003- Orthopaedic Biomechanics, Balgrist, Zurich.
2007 ISPO Annual Scientific Meeting, Stoke-on-Trent
2007- HipHub international conference, Leuven, Belgium.
Prize Winning Publications.
2004– Aircast Prize, British Association of Sport and Exercise Medicine
2004- Best paper International Society for Prosthetics and Orthotics
2007- Audi Design Foundation Award (supervisor to project).
2001- Best paper International Congress of Biomechanics.
Guest Editor- Medical Engineering & Physics.
2002 Co-editor Wiley Biomedical Engineering Encyclopaedia
2004-present: J Proc I Mech E Part H Journal of Engineering in Medicine
2005-present: Filtration, The journal of Medical and Life Science Filtration
2001-04 Clinical Biomechanics.
2003- Gait and Posture.
Learned Society Engagements.
2001-03 Chair- Biomedical Engineering Special Interest Group, Institute of Physics and Engineering in Medicine (IPEM).
2006 Advisory Committee, Tissue Engineering & Regenerative Medicine International Society
2007 TERMIS-EU Chapter Meeting, London,
2001-04: Member of EPSRC funded EQUAL network steering committee.
2004 IEE: Christmas Lectures for Schools in Scotland
2007- Royal Society Edinburgh Special Interest Committee (Engineering)
2001 Treasurer International Faculty for Artificial Organs.
2001-04 Corporate Membership Interview Panel (Biomedical Engineering), IMechE.
2006-present Advisory Board, Institute of Nano-Technology.
2001- Young Investigator Award Committee, International Society of Biomechanics.
2001-02: Institution of Mechanical Engineers- Engineering in Medicine Committee.
2006- IPEM Emerging Technologies Special Interest Group
Election to learned societies:
2002 Fellow, Institute of Electrical and Electronic Engineers
2004 Fellow, Royal Society of Edinburgh
2006 Fellow, Royal Society of Medicine
2004 Chartered Scientist, The Science Council
Royal Society for the Promotion of Health
Member of the Institute of Biology
2006 senior member IEEE.
2001 Companion Fellow British Orthopaedic Association.
Participation in review & funding bodies.
2002-2007 EPSRC Healthcare Panel Member
-2006 Reviewer for Swiss National Science Foundation.
2004 EPSRC Advanced Research Fellowships Sifting Panel
2005 Reviewer- Royal Society Wolfson Laboratory Refurbishment Grants
2004 The Gates Foundation- Panel Member Global Health Challenge Awards.
2004 Group for Translation Awards, The Wellcome Trust
2005 EPSRC/ BBSRC Stem Cell Initiative Review Panel
2007- BBSRC Review Panel (EBS)
2001-present: Reviewer for EPSRC, MRC, Action Medical Research, Wellcome Trust, National Science Foundation (USA), Austrian Science Fund.
2003-07: EPSRC(EQUAL) consortia awards panel.
2004, 2007: EPSRC reviewer of New Dynamics of Ageing grant call documentation.
2005-08: EPSRC/BBSRC Strategic Promotion of Ageing Research Capacity awards panel.
2007-2008: New Dynamics of Ageing Commissioning Panel
2006-present: Chair- Cardiovascular Devices Group, Health Technologies KTN.
2006-present: Research Project Monitor for DTI.
2001 Hong Kong University Grant Awards.
2001 EPSRC Interview Board- Advanced Fellowships in Engineering
2003, 2005 EPSRC Healthcare Grant Review Panel
2005- Engineering Panel, Science Foundation Ireland.
2003-07: Medical Engineering Advisory Panel, Action Medical Research.
2001-07: EPSRC Medical Engineering Prioritisation Panel.
2002 – Reviewer EPSRC
Government committees, advisory councils and boards for industry.
2002-03 British Homeopathic Association - Chair of Homeopathic Research Committee
2003-present: Associate Board Member - Medical Devices in Scotland
2004-2005: EPSRC Strategic Advisory Team – Engineering
2006-present: Health Technologies KTN Management Team
2001 Medical Devices Agency (MDA): Committee for the Safety of Medical Devices
2002-03 MDA: Committee for the Safety of Medical Devices Audit Group
2001-05 MDA: Committee for the Safety of Medical Devices
2005: Scottish Executive, Environment and Rural Affairs Department Review Panel: Impacts on Human Health.
2006-07 Medicines and Healthcare Regulatory Authority Expert Group- Biological Effects of Metal Orthopaedic Implants
2000-2003 Consultant- Amersham Health.
2004-present: Director of Science & Technology, IVMD Ltd.
EU Collaborative Research
GRANT & GAYLOR
2001-04: Partner Brite Euram Award
2006 International Patent Application PCT/GB2006/003671
2001-present: Patents in area of medical devices.(WO2007110625, US2007224604, EP1766399, EP11734862, US6866821, US6235491)
GRANT & GAYLOR
2002 Polymeric composition, European Patent Application 02090326.6
2003 International Patent Application PCT/EP 03/09885
2006: US7097663, Shoulder Prosthesis, Smith & Nephew.
Other Evidence of Esteem
2003-present External Examiner MSc Biomedical Engineering, University of Keele.
2003 Advisory panel ‘Tissue Engineering, Biochemical Engineering and Stem Cell Researchers Workshop’, Manchester Business School, University of Manchester
2003 Organised meeting Physical, Mathematical and Numerical Modelling of Blood Flow in Cardiovascular Disease, sponsors- IPEM, IMechE & Institute for Mathematics and its Applications
2003- MRC Discipline Hopping Award- (£50K)
2007 Chair plenary session on Cardiovascular Engineering, TERMIS-EU, London
2003-07: Invited participant to Annual International Spinal Research Trust Research Meetings.
2007: Invited participant- combined meeting of Christopher & Dana Reeve Foundation, Spinal Research and International Institute for Research in Paraplegia, Zurich.
2007: Session moderator, Copenhagen International Spasticity Workshop.
Visiting Professor, Faculty of Medicine, University of Northern Texas
Visiting Professor, Faculty of Medicine, University of Hong Kong
Visiting Scholar, University of Kirkkale, Turkey
2003: Member of Programme Committee and Session Chair on Brain Computer Interfaces, World Multi-conference on Systemics, Cybernetics and Informatics, Florida.
2003: MRC Discipline Hopping Award (£37K).
Industrial Support for Research
2000-02 Iontophoresis- Collaboration with Sysmex Corporation, Japan
2000-2003 Convatec (Bristol Myers Squibb)- wound hydration monitor development
2004-present In-Veritas Medical Diagnostics Ltd UK, non-invasive glucose monitoring.
2006-present : Unilever, Transdermal Skin Study
2007-2010: DTI, University of Brighton, Mast Carbons, Brightwake- Development novel nano-structured ceramic devices (£1.13M)
2007- Terumo Corp, £10K Annually.
2006-08 2 DePuy International Part-Funded PhD Studentships
2006-09 DePuy International EPSRC Case Studentship
2005-08 Organon, part funded PhD studentship
2002-05 Vascutek, PhD Studentship
2002 - DuPuy, Project funding 'Biomechanics of Deep Knee Bending'
2004- 2008: Stryker, PhD studentship
2004 - 2008: DuPuy, Funding to support MPhil studentships
2001– present Blatchford & Sons- supply of materials, prosthetic components and expertise (£15K ‘in kind’ annually).